Limb-threatening or critical limb ischemia (CLI) is manifested by Serious (much more than two weeks) ischemic relaxation agony, ischemic wounds or tissue loss, or gangrene in a single or both equally legs. Ischemic relaxation discomfort ordinarily occurs soon just after falling asleep; the affected individual is awakened by burning soreness https://www.sgvascularctr.com/treatment-of-peripheral-artery-disease-pad-in-singapore-a-comprehensive-guide/