Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors during the central anxious technique, conolidine modulates alternate molecular targets. A Science Innovations review observed that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabi... https://jareddzpes.kylieblog.com/39020122/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview